International Experts Urge Uniformity in Methotrexate Dosing for Psoriasis
An international consensus establishes dosing recommendations of methotrexate for psoriasis treatment and identifies current knowledge gaps on the topic.
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![There are no uniform guidelines regarding DMARD tapering. EULAR guidelines suggest RA pharmacotherapy should be de-escalated in the following order: glucocorticoids, biologic DMARDs, and, finally, conventional DMARDs, with each treatment stopping completely before de-escalation of the next agent in the sequence.[4] Numerous DMARD dose-tapering protocols have been studied, including immediate discontinuation of treatment. When the goal is to withdraw treatment, the ACR recommends an initial dose-tapering phase to enable better monitoring of patient response and candidacy for discontinuation.[5] The ACR also strongly encourages patient involvement in decisions regarding their individual DMARD tapering protocol.](https://www.dermatologyadvisor.com/wp-content/uploads/sites/20/2022/04/syringedrugsts53728911801_1026507.jpg)
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