Oral Acne Treatments

ORAL ACNE TREATMENTS
Generic Brand Strength Form Dose
ANTIBIOTICS
doxycycline 100mg tabs Adults: 100mg every 12hrs for 1 day, then 100mg/day in 1−2 divided doses; reduce dose after improvement
Acticlate 75mg, 150mg+ tabs6 Adults: 100mg every 12hrs, then 100mg daily (as a single dose or 50mg every 12hrs)
Children ≤8yrs: not usually recommended. >8yrs (<45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily in 1–2 divided doses; (≥45kg): use Adults dose
Doryx 50mg, 200mg del-rel tabs Adults: 200mg for 1 day (100mg every 12hrs), then 100mg daily (as a single dose or 50mg every 12hrs)
Children ≤8yrs: not usually recommended. >8yrs (≤45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily in 1–2 divided doses; (>45kg): use Adults dose
Doryx MPC 120mg del-rel tabs6 Adults: 120mg every 12hrs for 1 day, then 120mg daily (as a single dose or 60mg every 12hrs)
Children: ≤8yrs: not usually recommended. >8yrs (<45kg): 5.3mg/kg in 2 divided doses for 1 day, then 2.6mg/kg daily in 1–2 divided doses; (≥45kg): use Adults dose
Monodox 50mg, 75mg, 100mg caps Adults: 200mg for 1 day (100mg every 12hrs or 50mg every 6hrs), then 100mg daily (as a single dose or 50mg every 12hrs)
Children: ≤8yrs: not usually recommended. >8yrs (<45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily in 1–2 divided doses; (≥45kg): use Adults dose
Vibramycin 100mg caps Adults: 100mg every 12hrs for 1 day, then 100mg/day in 1−2 divided doses; reduce dose after improvement
25mg/5mL susp4
50mg/5mL syrup5
minocycline Dynacin 50mg, 75mg, 100mg caps Adults: 200mg once then 100mg every 12hrs; or 100−200mg once then 50mg four times daily. Children ≤8yrs: not recommended. >8yrs: 4mg/kg once then 2mg/kg (max 100mg) every 12hrs
Minocin 50mg, 100mg pellet-filled caps
Solodyn 55mg, 65mg, 80mg, 105mg, 115mg ext-rel tabs Adults: ≥12yrs: approximately 1mg/kg once daily for 12wks. Weight-based dosing (45–49kg): 45mg; (50–59kg): 55mg; (60–71kg): 65mg; (72–84kg): 80mg; (85–96kg): 90mg; (97–110kg): 105mg; (111–125kg): 115mg; (126–136kg): 135mg
tetracycline 250mg, 500mg caps Adults: initially 1g daily in 2−4 divided doses. After improvement: 125−500mg daily.
RETINOIDS
isotretinoin Absorica 10mg, 20mg, 25mg*, 30mg, 35mg, 40mg caps1 Adults: 0.5−1mg/kg/day in 2 divided doses; treat for ≤15−20wks if nodule count reduced by >70%; max 2mg/kg/day. Repeat course only if necessary after ≥2mos drug-free interval.
Amnesteem 10mg, 20mg, 40mg caps1
Claravis 10mg, 20mg, 30mg, 40mg caps1,2
CONTRACEPTIVES
drospirenone/
ethinyl estradiol
Loryna 3mg/20mcg (24 tabs); inert (4 tabs) tabs Women ≥14yrs old: 1 tab daily for 28 days; repeat
Yaz tabs
drospirenone/
ethinyl 
estradiol/
levomefolate calcium
Beyaz 3mg/20mcg/
 
0.451mg (24 pink); levomefolate 0.451mg (4 light orange)
tabs Women ≥14yrs old: 1 tab daily for 28 days; repeat
norethindrone acetate/
ethinyl estradiol
Estrostep Fe 1mg/20mcg (5 tabs) + 1mg/30mcg (7 tabs) + 1mg/35mcg (9 tabs); inert (7 tabs); ferrous fumarate 75mg tabs Women ≥15yrs old: 1 tab daily for 28 days; repeat
Tilia Fe tabs
Tri-Legest Fe tabs
norgestimate/
ethinyl estradiol
Ortho Tri-Cyclen 28 0.18mg/35mcg (7 tabs) + 0.215mg/35mcg (7 tabs) + 0.25mg/35mcg (7 tabs); inert (7 tabs) tabs Women ≥15yrs old: 1 tab daily for 28 days; repeat
Tri-Previfem tabs
Tri-Sprintec tabs
NOTES

Key: + = scored tablets; *contains tartrazine

1contains soy; 2contains vitamin E; 3contains parabens; 4raspberry flavor; 5as calcium, raspberry-apple flavor; contains sulfites; 6contains sodium

(Rev. 9/2018)

This article originally appeared on MPR