Working Core Outcome Set Aims to Improve Cutaneous Lupus Erythematosus Clinical Trials
Researchers developed a working core outcome set with the objective of improving clinical studies in cutaneous lupus erythematosus.
Systemic Lupus Erythematosus
Case Report: Chilblain Lupus-Like Cutaneous Reaction in Patient Receiving ICI Treatment for Oropharyngeal Cancer
In a letter to the editor, authors reported the case of chilblain lupus-like cutaneous reaction that fulfilled the criteria for systemic lupus erythematosus in a patient who received treatment with immune checkpoint inhibitors for oropharyngeal cancer.
Megakaryocyte Expansion May Contribute to Pathogenesis of Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Primary Sjögren Syndrome
Researchers identified the transcriptional profile and composition of immune cells in the peripheral blood of patients with rheumatoid arthritis, systemic lupus erythematosus, and primary Sjögren syndrome.
Psoriasis and Risk for Lympho-Hematological Malignancies
The association between psoriasis and lympho-hematological malignancies in 25 observational cohort studies is evaluated.
Frontal Fibrosing Alopecia May Develop Earlier and Progress Faster in Black Women
The differences in presentation of frontal fibrosing alopecia (FFA) in black women and white women was investigated.
Data Lacking on Biologic and JAK Inhibitor Therapies for Pediatric Rheumatology Patients
Randomized, controlled trials in pediatric inflammatory rheumatic diseases (PiRDs) of patients who underwent bDMARDs and JAK inhibitors are reviewed.
Anifrolumab Improves Skin and Joint Disease Activity in Patients With Systemic Lupus Erythematosus
According to data from a press release, which were later presented at the EULAR 2021 Virtual Congress, “Anifrolumab was consistently associated with improvements in both skin rash and arthritis across three different disease measures…in patients with moderate to severe SLE.”
BIIB059 Safe and Effective in Reducing CLE Activity Regardless of SLE
The efficacy of BIIBO59 in patients with cutaneous lupus erythematosus with and without concomitant systemic lupus erythematosus during 16 weeks was evaluated.
Lower Income Associated With Poorer Quality of Life in Patients With Cutaneous Lupus Erythematosus
Researchers studied the effect of income on quality of life in patients with cutaneous lupus erythematosus.
SLE Patients, Regardless of Comorbid CV Disease, Have Blunted Microvascular Reactivity
Skin microvascular function was assessed via laser speckle contrast analysis (LASCA) in patients with SLE, with and without cardiovascular disease and risk factors.
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