Dupilumab Shows Rapid and Sustained Improvement in Atopic Dermatitis-Associated Itch in Adults, Adolescents
Improvements in itch were seen within days of treatment initiation of dupilumab in patients with atopic dermatitis, and were sustained.
Pruritus
Adjuvant Therapies May Influence Dupilumab’s IGA Response Rates in AD
Treatment with dupilumab in patients with moderate to severe atopic dermatitis was found to be effective in 54% of patients—a percentage that may reflect use of adjunctive therapies.
Ruxolitinib Cream May Reduce Itch, Increase QoL in Atopic Dermatitis
Rapid and sustained alleviation in itch was observed with 1.5% ruxolitinib cream twice daily, which corresponded with reduced QoL burden.
Depression and Suicidal Ideation Strongly Linked to Presence of Itch
Considering the strong association with mental health health issues and itch, a comprehensive care approach may be best for patients with pruritus.
Pruritus, Noncancerous Tumors More Common in the Geriatric Population
The geriatric population has unique dermatologic needs and concerns, which differ greatly from those of younger patients, study research finds.
Effective Dandruff Relief Provided by Shampoo Containing Zinc Pyrithione and Medium Fatty Chain Acid
Notable improvements in adherent scalp flaking and pruritus in patients with moderate dandruff may position a shampoo as the new generation of treatment for adherent dandruff.
Tradipitant Misses Primary End Point in Atopic Dermatitis Trial
Results showed that patients with mild atopic dermatitis did see significant improvement in pruritus.
Off-Label Prescribing in Dermatology
The off-label use of treatments is especially prevalent in dermatology as the need for effective therapies outpaces the approval process. Experts discuss the most commonly employed treatments, the ethical implications of off-label use, and the need for patient education.
Elevated Kallikrein 7 Expression Tied to Itch in Atopic Dermatitis
An emerging paradigm in itch biology is supported by findings that suggest KLK7 as an influence in the disease pathogenesis of atopic dermatitis.
PIQ Short Forms Show Good Validity in Assessment of Itch in Adults With AD
The new Patient-Reported Outcomes Measurement Information System (PROMIS) Itch Questionnaire (PIQ) short forms may have application in clinical trial and practice.
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