Deep Learning Models for Skin Cancer Detection
With rapid advances in the use of machine learning in the past several years, there have been exciting developments in the field of dermatology.
Melanoma
Complete Lymphadenectomy in Melanoma: No OS Benefit Found
Female gender and ulceration were among the variables found to be predictive of a positive CLND in patients with melanoma characterized by a positive sentinel lymph node.
BRAF Plus MEK Inhibition Appears Less Well Tolerated Following Immune Checkpoint Blockade in Patients With Melanoma
In this study, approximately one-third of patients receiving the combination of a BRAF and a MEK inhibitor following anti-PD-1 therapy required hospitalization due to an adverse event.
BiTE® Antibody Constructs and Treatment-Resistant Metastatic Melanoma
Investigators examined CDH19 and DLL3 expression and corresponding BiTE® antibody constructs activity in a panel of 14 melanoma cell lines that originated from patients who were resistant to either targeted therapy or immune checkpoint therapy.
Incidence, Site of Pediatric Melanoma Different Among Male and Female Adolescents and Young Adults
Researchers in Colorado reviewed data on melanoma in pediatric patients 10 to 19 years, finding sex-specific differences in anatomic site and incidence of the disease.
Primary Histologic Subtype an Independent Predictor of Survival in Melanoma
A comparison study of the tumor molecular profiles of NM and SSM sought to explain the distinctly different prognoses among patients with either of these 2 histologic subtypes.
Race, Dermatologist Density Affect Melanoma Survival Rates
Factors positively associated with MIR included dermatologist density, percent of the population that is non-Hispanic white, and average household income.
Melanoma Survival Varies By State in US
U.S. states with more physicians and a larger percentage of non-Hispanic whites have worse melanoma survival.
Nomogram Predicts Melanoma Recurrence Risk After Negative Sentinel Node Biopsy
Current treatment guidelines do not adequately cover what kind of surveillance and treatment should apply to patients with melanoma after a negative sentinel node biopsy.
High Melanoma Care Costs With Ipilimumab
Melanoma costs have increased as a result of the introduction of ipilimumab.
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