Camrelizumab, Apatinib, Temozolomide Combination Is Efficacious for Acral Melanoma
In all, 32 patients had a response, translating to an ORR of 66.7%.
Melanoma
Toripalimab With Axitinib Active in Treatment-Naive Advanced Mucosal Melanoma
Patients were stratified by programmed death ligand 1 status and randomly and evenly assigned to 3 treatment groups.
Concurrent Therapy Improves Responses, Increases Toxicity in Stage III Melanoma
The higher response rates with concurrent therapy did not translate to improvements in survival.
Higher Fish Intake May Increase Melanoma Risk
Higher total fish intake is associated with increased risk for malignant melanoma and melanoma in situ.
Skin Cancer Awareness Month: Protection Is Prevention
Patient awareness of sun damage doesn’t always translate into safer sun practices, finds Lisa Nyanda-Manola, MD. She describes how she counsels her patients, especially those with skin of color, to protect themselves.
Immune Checkpoint Inhibitors and Adverse Events in Older Patients With Melanoma
Researchers sought to investigate the connection between immune checkpoint inhibitors (ICIs) and immune- and autoimmune-related adverse events in older patients diagnosed with melanoma.
Second-Line Targeted Therapy Beneficial for PD-1 Resistant Melanoma
The outcome of second-line targeted therapy after progression on PD-1-based immunotherapy in patients with BRAFV600-mutant melanoma is examined.
Pembrolizumab a Successful Adjuvant Treatment for Patients With High-Risk Melanoma
Recurrence-free survival in patients with melanoma treated with pembrolizumab are reported.
White Patients May Be Overdiagnosed With Melanoma
Data from the Surveillance, Epidemiology, and End Results (SEER) program are used to compare melanoma incidence and mortality trends among Black and White patients from 2014 to 1975.
Combo Appears Effective After Anti-PD-1 Failure in Advanced Melanoma
Ipilimumab plus nivolumab demonstrated efficacy in a phase 2 trial of patients with advanced melanoma who failed prior anti-PD-1 therapy.
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