Melanoma Archives - Dermatology Advisor

Pilocytic astrocytoma is a slow growing, relatively well-defined tumor that develops in the cerebrum, optic nerve pathways, brain stem, and cerebellum. It occurs most often in children and teens.2

Past Decade Has Seen Improved Outcomes in Melanoma Brain Metastasis

By

Colby Stong

April 13, 2021

A team of investigators sought to assess the impact of multimodality, CNS-directed treatments on survival rates in patients with melanoma brain metastasis.

Circulating tumor DNA conveyed prognosis among patients with high-risk stage III melanoma, reinforcing the need to include this measure in clinical trial design.

Skin Cancer

Blood Cell Score for Identifying Aggressive Melanoma

By

Leah Lawrence

April 7, 2021

A team of investigators created the myeloid index score, which captures the prognostic value of blood myeloid cells and may be used in the management of patients with melanoma.

Skin Cancer

Patient Age, Melanoma Location, Affect Risk for Radio-Induced Complications

By

K. Patricia Bouweraerts, MA

April 6, 2021

Posterior uveal melanoma had greater risk for radiation retinopathy and papillopathy.

Skin Cancer

High-Risk Clinic for Melanoma Surveillance Is Scalable

April 5, 2021

A structured surveillance program for high-risk melanoma patients can be scaled and successfully replicated even in a primary care skin cancer clinic.

Photomicrograph of a lymph node showing malignant melanoma.

Skin Cancer

Patterns in the Development of Melanoma Across Body Sites

By

Vicki Moore, PhD

April 1, 2021

A team of international researchers sought to confirm a “dual pathway hypothesis” for the development of melanoma.

Skin Cancer

Immunotherapy May Put Men With Melanoma at Risk for Low Testosterone

By

Christina Bennett, MS

March 29, 2021

A team of investigators sought to assess the impact of immunotherapy for malignant melanoma on testosterone levels, as well as to identify risk factors for low testosterone.

As post-transplant medications are used to reduce the body’s immune reaction to a foreign organ, the

Skin Cancer

Increased Risk of Skin Cancer Linked to Long-Term Use of Certain Diuretics

By

Christina Bennett, MS

March 26, 2021

A team of investigators sought to assess the relationship between thiazides, thiazide-like diuretics, or calcium channel blockers and the development of basal cell carcinoma, squamous cell carcinoma, or cutaneous malignant melanoma.

Immunotherapy Increasingly Used in Cancer Care

Skin Cancer

Neoantigen Vaccine for Melanoma Reaches Beyond Its Target

By

Julia Faith Sklar

March 18, 2021

Study reports that a personalized, long-peptide vaccine that can target up to 20 personal neoantigens per patient has been successful in preventing melanoma in patients at high risk for recurrence.

Skin Cancer

Cavrotolimod Designated Orphan Drug for Merkel Cell Carcinoma

By

Diana Ernst, RPh

March 17, 2021

Cavrotolimod is a toll-like receptor 9 agonist that is designed to induce anticancer immune responses through proprietary spherical nucleic acid (SNA™) technology.

New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.

Skin Cancer

Nomogram Developed to Guide Management of Thin Melanomas

By

Leah Lawrence

March 16, 2021

Using readily available clinicopathologic information, a team of investigators developed a risk calculator to predict disease recurrence in patients with thin melanomas.