Skin Cancer Latest News Archive

Skin Cancer

Mohs Surgery Alone Associated With Improved Outcomes in High-Risk Squamous Cell Carcinoma

By November 26, 2018

The investigators reported the rates of poor outcomes in patients with hrSCC treated with MMS alone, and explored specific clinical factors that may be more predictive of these outcomes.

Skin Cancer

Higher Concentration, Fewer Applications of Resiquimod Gel Effective for Actinic Keratosis Treatment

By November 21, 2018

The use of resiquimod gel 0.03%/0.01% is effective for the treatment of patients with actinic keratosis.

Skin Cancer

Coordinated Care Needed for Cancer Survivors, Caregivers

November 15, 2018

There is an urgent need for coordinated, comprehensive, personalized care for cancer survivors and caregivers.

Skin Cancer

Poll: Patients, Caregivers Worry About Cost of Cancer Care

November 12, 2018

In addition to fear of pain and suffering, Americans worry about cancer-related expenses.

Skin Cancer

Cancer Mortality Up for 2nd-, 3rd-Generation Latino Immigrants

November 09, 2018

Second- and third-generation Latino immigrants have an increased risk for cancer mortality compared with first-generation Mexico-born immigrants.

Skin Cancer

Actinic Keratosis Treatment Cost Burdensome for Medicare Fee-for-Service Participants

By November 07, 2018

Data showed fluctuations in Healthcare Common Procedure Coding System claims prices, allowable charges for actinic keratosis destruction, and Medicare payments for these charges.

Skin Cancer

Predictors of Outcomes in Elderly With Mycosis Fungoides and Sézary Syndrome

By November 07, 2018

Older age at the diagnosis of mycosis fungoides and Sézary syndrome is not predictive of worse disease-specific outcomes.

Skin Cancer

Risk for Nevus Development in Children Aged 3 to 16 Years

By November 05, 2018

Researchers examine nevus development in children age 3 to 17 years to analyze acquisition patterns for total nevus counts and counts on body sites exposed to ultraviolet light.

Skin Cancer

Cancer Survival Higher in Teens, Young Adults Than Other Groups

October 30, 2018

Overall, cancer survival among adolescents and young adults has consistently exceeded that of other age groups except during the HIV/AIDS epidemic.

Skin Cancer

Organic Food Consumption and Cancer Risk: What's the Link?

By October 29, 2018

To investigate the link between organic food consumption and cancer risk, study authors conducted a population-based prospective cohort study among French adults.

Skin Cancer

Gentian Violet Induces Apoptosis and Proliferation of Cutaneous T-Cell Lymphoma

By October 26, 2018

Researchers analyzed 1710 compounds through high-throughput small molecule screening and observed their interactions with CTCL cells.

Skin Cancer

Cutaneous Squamous Cell Carcinoma Risk Associated With Voriconazole Use

By October 26, 2018

The systematic literature review and meta-analysis were conducted to clarify the association between voriconazole use and SCC risk.

Skin Cancer

Pembrolizumab May Be Effective for Advanced Basal Cell Carcinoma

By October 15, 2018

Investigators examined the effects of intravenous pembrolizumab with or without vismodegib for individuals with advanced basal cell carcinoma.

Skin Cancer

Inconsistent Association Between Malignant Melanoma and In Vitro Fertilization

By Dermatology Advisor Contributing Writer October 04, 2018

Women included in the studies had been diagnosed with infertility, defined as the inability to conceive for >12 months or another similar reproductive disorder.

Skin Cancer

First Treatment for Advanced Cutaneous Squamous Cell Carcinoma FDA-Approved

By October 01, 2018

The approval was based on data from 2 open-label studies where patients with metastatic CSCC or locally advanced CSCC who were not candidates for curative surgery or curative radiation received Libtayo 3mg/kg intravenously every 2 weeks for up to 48 weeks or up to 96 weeks until disease progression, unacceptable toxicity, or completion of planned treatment.

Skin Cancer

Novel Immunotherapy May Increase Survival in Melanoma With Brain Metastases

October 01, 2018

Checkpoint blockade immunotherapy (CBI) is associated with significant increases in overall survival (OS) in a real-world population of patients undergoing treatment for melanoma brain metastases (MBM).

Skin Cancer

Facial-Aging App May Help Encourage Skin Cancer Prevention

By September 24, 2018

Of the 119 individuals who tried the app, 105 noted that the intervention encouraged them to increase their sun protection.

Skin Cancer

Age, Education Predict Skin Protection Following Melanoma Diagnosis

By September 21, 2018

Participants with a history of melanoma with inadequate sunscreen use doubled their risk for another primary melanoma within the next 2 years.

Skin Cancer

Review: Treatments for Primary Basal Cell Carcinoma Compared

September 21, 2018

For patients with primary basal cell carcinoma, estimated recurrence rates are similarly low for excision, Mohs surgery, curettage and diathermy, and external-beam radiation.

Skin Cancer

Keytruda Gets Priority Review for Merkel Cell Carcinoma Indication

September 05, 2018

Merkel cell carcinoma is a rare form of skin cancer associated with higher mortality rates than other skin cancers.

Skin Cancer

Experiencing Parental Cancer As Child Has Lasting Impact

September 04, 2018

Individuals who experience parental cancer as children or adolescents have a higher risk of low educational attainment and attenuated income at age 30 years.

Skin Cancer

Time to Stop Cancer Screenings: What Do Patients Want to Hear?

August 28, 2018

Older adults prefer explanations about stopping cancer screening that emphasize the shift to focus on other health issues.

Skin Cancer

Similar Outcomes for Rural, Urban Cancer Patients in SWOG Trials

August 27, 2018

Rural and urban cancer patients with uniform care access through participation in a SWOG treatment trial have similar outcomes.

Skin Cancer

Predictive Scoring Model Effectively Differentiates Between Subungual Melanoma in Situ, Longitudinal Melanonychia

By August 21, 2018

A predictive scoring model that incorporated dermoscopic characteristics of SMIS was evaluated.

Skin Cancer

Dermatologist Intervention Tied to Better Sun Protection

August 15, 2018

A brief intervention delivered by dermatologists is associated with improvements in patients' sun protection behavior as well as their satisfaction with dermatologists' communication.

Skin Cancer

Physician Communication Linked to Improved Patient-Reported Outcomes in Actinic Keratosis

By August 13, 2018

Overall, 961 participants had received a prescription for ingenol mebutate; 175 received either diclofenac 3% in hyaluronic acid or imiquimod 5%.

Skin Cancer

Early Identification of Nail Unit Melanoma Leads to Good Prognosis

By August 03, 2018

Investigators examine epidemiologic, histologic, and clinical features of in situ nail unit melanoma.

Skin Cancer

Complementary Medicine Use Ups Refusal of Usual Cancer Therapy

July 25, 2018

Patients with cancer who receive complementary medicine are more likely to refuse conventional cancer treatment.

Skin Cancer

Hand-Holding, Stress Ball Don't Cut Anxiety in Skin CA Removal

July 25, 2018

Hand-holding and squeezing a stress ball do not provide anxiety reduction among patients during excisional removal of non-melanoma skin cancer.

Skin Cancer

Overall Cancer Mortality Rates Decreasing for Men and Women

July 24, 2018

Cancer incidence rates have decreased among men but remained stable among women, while cancer death rates are decreasing for both men and women.

Skin Cancer

Australian Researchers Develop First Blood Test for Melanoma

July 20, 2018

The first blood test to detect melanoma skin cancer in its early stages has been created.

Skin Cancer

Topical Hydrogen Peroxide Safe, Effective for Resolution of Seborrheic Keratoses

By July 13, 2018

The investigators sought to evaluate the efficacy and safety of HP40 vs a vehicle for the treatment of seborrheic keratoses.

Skin Cancer

Skin Cancer Education May Improve Sun Protection Practices Among Organ Transplant Recipients

By July 12, 2018

The use of multiple sun protection measures was defined as the use of 2 or more of these measures more than 50% of the time when the individual was outdoors.

Skin Cancer

Patient Interest Fairly High for Melanoma Genetic Risk Testing

July 12, 2018

Reduced interest seen in minority and less educated populations

Skin Cancer

No Increased Risk for Venous Thromboembolism in Keratinocyte Carcinoma

By July 11, 2018

The investigators sought to determine the risk for VTE among patients with KC compared with that among individuals not diagnosed with cancer and among those with common malignant neoplasms associated with VTE.

Skin Cancer

UV Protection Methods Low in Individuals With Skin of Color

July 09, 2018

Many individuals with skin of color do not know that they need comprehensive photoprotection to prevent skin cancer and photoaging.

Skin Cancer

WHO Calls for Renewed Effort to Combat Chronic Disease

July 09, 2018

The World Health Organization Independent High-Level Commission has proposed six recommendations to address the growing epidemic of non-communicable diseases.

Skin Cancer

Melanoma Risk Differs in Men, Women With MC1R Variants

By July 06, 2018

Further investigation might eventually lead to sex-dependent prevention strategies and appropriate therapy.

Skin Cancer

Decision Tree Model Can ID Behaviors Linked to Sunburn Risk

July 05, 2018

A decision tree analytic technique shows the interactive effects of sun protective behaviors on the likelihood of sunburn.

Skin Cancer

FDA Accepts sBLA for Pembrolizumab as Adjuvant Therapy for Melanoma

June 25, 2018

If approved, the new indication could mean pembrolizumab could be used for patients with melanoma.

Skin Cancer

Imiquimod Cream Reduces Margins for Lentigo Maligna Excision

By June 25, 2018

Without imiquimod, the staged excision of lentigo maligna can often require multiple stages and result in significant cosmetic morbidity.

Skin Cancer

#DontFryDay: 12 Million Twitter Impressions Spread Message of Sun Safety

By June 21, 2018

Social media is an ideal platform to reach teenagers and young adults to encourage sun safety.

Skin Cancer

Sun Defenses Up in Transplant Patients After Skin Cancer Study

June 19, 2018

For organ transplant recipients, participation in a skin cancer research study is associated with increased use of multiple sun protection behaviors.

Skin Cancer

AJCC Cancer Staging Manual 8th Edition Improves on Reproducibility, Concordance in Melanoma Staging

By June 14, 2018

Although the AJCC 8 has improvements compared with AJCC 7, concordance and reproducibility remain low.

Skin Cancer

Skin Cancer Examinations More Likely for Indoor Tanning Users

June 11, 2018

Engaging in ultraviolet indoor tanning is associated with increased use of skin cancer examinations.

Skin Cancer

Smartphone App Effectively Teaches Visual Diagnosis of Melanoma

By June 08, 2018

A smartphone application is a more effective learning tool for accurately diagnosing melanoma compared with traditional, rule-based methods.

Skin Cancer

Facial Morphing Program May Deter Young Adults From Tanning

June 05, 2018

Researchers examined the efficacy of an appearance-based facial morphing program for reducing intentional ultraviolet exposure among individuals at risk for skin cancer.

Skin Cancer

FDA Warns Companies Promoting Ineffective "Sunscreen Pills"

By June 04, 2018

Alternative sun protection products, including pills and dietary supplements, are misleading consumers through false marketing and advertising.

Skin Cancer

Convolutional Neural Network Tops Clinicians for Melanoma ID

June 04, 2018

Researchers trained and validated Google's Inception v4 CNN architecture using dermoscopic images and corresponding diagnoses.

Skin Cancer

Risk for Cutaneous Squamous Cell Carcinoma Increased With Photosensitizing Antihypertensive Drugs

By May 29, 2018

With the knowledge that many ADs are photosensitizing, the investigators sought to examine the association between AD use and risk for cSCC among a cohort of non-Hispanic white patients with hypertension.

Skin Cancer

Teledermatology Could Expedite Care for Suspected Skin Cancer

May 16, 2018

Researchers compared the costs of teledermoscopy referral (electronic referral containing digital dermoscopic images) versus usual care (a written referral letter) for specialist dermatologist review of a suspected skin cancer.

Skin Cancer

Improved Classification of Melanocytic Nevi Using BRAF V600E Expression

By May 15, 2018

The investigators retrospectively identified melanocytic nevi from their laboratory reporting system in the department of dermatology at the University of California, Davis, in Sacramento.

Skin Cancer

Nodal Metastasis Risk Up When Cancer Is Directly on the Lip

May 14, 2018

The risk of nodal metastasis is five-fold greater for skin cancer on the vermilion lip versus the cutaneous lip.

Skin Cancer

SLNBs Feasible After Wide Local Excisions in Melanoma of the Head and Neck

By May 07, 2018

Sentinel nodes were accurately identified in all 30 patients who underwent WLE.

Skin Cancer

Knowledge Not Tied to Addictive Tanning Behavior in Millennials

May 04, 2018

For millennials, sun protection knowledge is not associated with addictive tanning behavior.

Skin Cancer

Tafinlar + Mekinist Approved for Adjuvant Tx of Melanoma With BRAF V600 Mutation

By May 03, 2018

Approval was based on COMBI-AD, an international, multi-center, randomized, double-blind, placebo-controlled trial in 870 patients with Stage III melanoma with BRAF V600E or V600K mutations, and pathologic involvement of regional lymph node(s).

Skin Cancer

Specific Healthcare Interventions Are Needed to Promote Skin Health Among Indoor Tanners

By May 03, 2018

In terms of skin cancer screening, 30.18% of indoor tanners and 19.52% of nontanners had received screening.

Skin Cancer

Link Between Chronic Aspirin Use and Malignant Melanoma

By May 02, 2018

Further investigation into the link between chronic, once-daily aspirin use and malignant melanoma is warranted.

Skin Cancer

Increased Risk for Skin Cancer Among HIV-Infected Individuals

By April 30, 2018

The risk for skin cancer was examined in patients with HIV infection.

Skin Cancer

Males With BRCA Mutations Have Increased Risk of Certain Cancers

April 23, 2018

Males with BRCA mutations have increased incidence of malignant disease, specifically prostate, melanoma, pancreas, and breast cancers.

Skin Cancer

Marital Status Tied to Earlier Presentation of Melanoma

April 18, 2018

For patients with localized melanoma, marital status is associated with earlier presentation.

Skin Cancer

Adjuvant Pembrolizumab Beneficial in Stage III Melanoma

April 18, 2018

Pembrolizumab is associated with significantly longer recurrence-free survival than placebo as adjuvant therapy for high-risk stage III melanoma.

Skin Cancer

Melanoma, Nonmelanoma Skin Cancer Associated With Reduced Risk for Alzheimer's

By April 18, 2018

Additional examination of these relationships is warranted to help clarify the complex biologic and psychosocial interactions among Alzheimer disease, malignant melanoma, and nonmelanoma skin cancer.

Skin Cancer

Melanocytic Skin Lesions Best Interpreted By Experienced, Specialized Pathologists

By April 13, 2018

Pathologist characteristics, including level of experience and training, were analyzed in association with these assessments using multivariable logistic regression modeling.

Skin Cancer

Few Indoor Tanners Have Been Screened for Skin Cancer

April 06, 2018

About 30 percent of indoor tanners have been screened for skin cancer, with correlates of screening including older age, history of melanoma or skin cancer, and use of very high sun protection factor sunscreen use.

Skin Cancer

Tumor-Infiltrating Lymphocytes Predict Melanoma Prognosis in Men

By April 05, 2018

The study may be limited by misclassification bias resulting from potential variability in tumor-infiltrating lymphocyte (TIL) classification, as well as selection bias resulting from the inclusion of only patients with TIL data.

Skin Cancer

Indoor, Sunless Tanning More Common Among Sexual Minority Men

By April 05, 2018

Because sexual minority men show increased rates of skin cancer, investigators performed a cross-sectional analysis on data from the 2015 National Health Interview Surveys.

Skin Cancer

Encorafenib, Binimetinib May Be Effective in BRAF-Mutant Melanoma

By April 02, 2018

One death possibly related to treatment was, however, noted in the combination group.

Skin Cancer

Self-Examination Key to Fewer Follow-Up Visits After Melanoma Excision

By March 29, 2018

Higher stage of disease, having melanoma on a limb, living with others rather than living alone, not having private health insurance, and consulting with a specialist for another chronic medical condition were independently associated with a preference for fewer follow-up visits.

Skin Cancer

Hydrochlorothiazide Tied to Nonmelanoma Skin Cancer Risk

March 27, 2018

Use of the diuretic hydrochlorothiazide is associated with a substantially increased risk of non-melanoma skin cancer.

Skin Cancer

Strong Social Networks Benefit Teen Cancer Survivors

March 23, 2018

Researchers found that survivors were found to have more available resources for emotional support, tangible support, physical activity advice, and weight management advice vs the controls.

Skin Cancer

No Survival Benefit in Melanoma With Adjuvant Vemurafenib

By March 15, 2018

Vemurafenib adjuvant therapy does not improve disease-free survival among patients with resected stage IIC to IIIB melanoma.

Skin Cancer

Sentinel Node Biopsy vs Breslow Thickness for Melanoma Prognosis: Which is Better?

By March 09, 2018

Both Breslow thickness and sentinel lymph node status were statistically significant in predicting cutaneous melanoma.

Skin Cancer

FDA Approves New Opdivo Dosing for Metastatic Melanoma, Squamous Cell Carcinoma

By March 08, 2018

The FDA has approved a supplemental Biologics License Application to include a new dosing schedule for a nivolumab treatment as a 480 mg infusion given 4 weeks for a majority of its indications.

Skin Cancer

Skin Neoplasia Prevention Possible With 6-HAP-Producing S epidermidis

March 06, 2018

Strains of Staphylococcus epidermidis producing 6-N-hydroxyaminopurine may provide protection against skin neoplasia.

Skin Cancer

Dermoscopic Criteria for Diagnosing Melanoma in Situ Identified

February 28, 2018

Researchers evaluated dermoscopic images of melanoma in situ and other flat pigmented skin tumors for the presence of predefined criteria.

Skin Cancer

Obesity Associated With Greater Survival in Metastatic Melanoma

February 23, 2018

For men with metastatic melanoma treated with targeted or immune therapy, obesity is associated with improved survival.

Skin Cancer

Predictors of Treatment Response in Actinic Keratosis Treated With Ingenol Mebutate 0.015% Gel

By February 22, 2018

The investigators aimed to determine whether dermoscopic features were able to predict treatment response to ingenol mebutate 0.015% gel for actinic keratosis.

Skin Cancer

Indoor Tanning: Fathers May Not Perceive Harms for Teens

February 22, 2018

Parents who had never received skin cancer prevention counseling from their child's health care provider more often perceived low harms of adolescent indoor tanning.

Skin Cancer

Risk for Melanoma Linked to Iris Pigmented Lesions

By February 12, 2018

The study findings suggest that a detailed dermatologic examination for melanoma may be reasonable in individuals <40 years of age with iris pigmented lesions.

Skin Cancer

Recurring Actinic Keratosis Reduced With Topical Fluorouracil vs Topical Imiquimod

By February 08, 2018

Treatment with 5-FU was associated with a significant reduction in the short-term incidence of subsequent actinic keratosis.

Skin Cancer

Increased Melanoma Incidence Among Non-Hispanic Whites

February 08, 2018

In recent years there has been an increase in melanoma incidence, with more than 70% of melanomas diagnosed among those aged 55 years and older.

Skin Cancer

Squamous Cell Carcinoma Classification Improved With AJCC8 Revision

By February 06, 2018

The 8th edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual demonstrates improved homogeneity and monotonicity compared with the 7th edition.

Skin Cancer

Global Cancer Survival Trends Generally Increasing

February 06, 2018

Worldwide, survival trends for cancer are generally increasing, although there is considerable global variation in survival rates.

Skin Cancer

SPF 100+ Superior to SPF 50+ for Preventing Sunburn

By January 29, 2018

Sunburn severity was significantly less with SPF 100+ vs SPF 50+ sunscreen.

Skin Cancer

Immunotherapy Efficacy in Malignant Melanoma Not Affected by Age

By January 25, 2018

Patients older than 65 had better median progression-free survival and overall survival than those 65 or younger.

Skin Cancer

Incidence of Squamous Cell Carcinoma on the Eyelid Increasing in England

January 25, 2018

Researchers performed a comprehensive review of squamous cell carcinoma cases in England and noted a rise in eyelid carcinomas over the last decade.

Skin Cancer

Desmoplastic Melanomas Have High Response Rate to PD-1 Blockade

January 23, 2018

Patients with desmoplastic melanoma have a high level of objective tumor response to treatment with antibodies to block programmed cell death 1 (PD-1) or PD-1 ligand (PD-L1).

Skin Cancer

Specific Oral Bacteria May Reduce Risk for Squamous Cell Carcinoma

By January 17, 2018

The findings may have implications for cancer prevention.

Skin Cancer

Risk for Basal, Squamous Cell Carcinoma Linked to Hydrochlorothiazide

January 11, 2018

Hydrochlorothiazide use is associated with an increased risk of non-melanoma skin cancer, with evidence of a dose-response relationship.

Skin Cancer

Surgery for Squamous Cell Carcinoma Reduced With Fluorouracil Cream

January 10, 2018

Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for 1 year among patients with a history of keratinocyte carcinomas.

Skin Cancer

Laser Therapy Improves QOL in Radiation-Induced Breast Telangiectasia

January 09, 2018

Laser monotherapy improves health-related quality of life in female patients with radiation-induced breast telangiectasias.

Skin Cancer

Subset of Metastatic Melanoma Patients May Be Cured With Pembrolizumab

By January 08, 2018

Pembrolizumab leads to a durable complete response with low rates of relapse — even 2 years after discontinuation — and may cure a subset of patients with metastatic melanoma.

Skin Cancer

FDA Approves Nivolumab as Adjuvant Treatment for Metastatic Melanoma

By January 04, 2018

The FDA has approved an adjuvant treatment for patients with melanoma with lymph node involvement or metastatic disease who have undergone complete resection.

Skin Cancer

Distinct Pattern of Shiny White Streaks Highly Specific for Melanoma Diagnosis

By December 21, 2017

Patients presenting with lesions with shiny white streaks on dermoscopy should undergo biopsy for possible melanoma.

Skin Cancer

Photodynamic Therapy Safe, Effective for Actinic Keratoses

By December 18, 2017

Over 90% of patients and clinicians would consider using photodynamic therapy again if needed.

Skin Cancer

Diligent Skin Cancer Screenings May Help Manage Squamous Cell Carcinoma Risk in Solid Organ Transplant Recipients

By December 12, 2017

Transplant recipients developed squamous cell carcinomas that did not appear to behave more aggressively than those that developed in the immunocompetent group.

Skin Cancer

Melatonin Derivatives May Have Antitumor Properties in Melanoma

By December 12, 2017

Researchers examined the changes in levels of different proteins in cancer cell lines after treatment with melatonin analogues

Skin Cancer

Collaborative Approach Improves Adoption of Sun Safety Policies in School Districts

By December 04, 2017

Future efforts should recognize that larger school districts may require a more personalized policy than smaller ones.

Skin Cancer

Survival Benefit in Advanced Melanoma With Pembrolizumab vs Ipilimumab

By December 01, 2017

Fifty-five percent of patients treated with pembrolizumab survived through 24-months compared with 43% of patients treated with ipilimumab.

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