A small study on patients with metastatic melanoma who were treated with autologous vaccines in a phase 2 clinical trial suggests that soluble PD-1 may have potential as a prognostic biomarker.
Weightbearing areas indicating mechanical stress are correlated with a higher number of plantar melanoma and also show a tendency to manifest as invasive melanomas at diagnosis more frequently than in non-weightbearing areas.
Researchers investigated the use of artificial intelligence to evaluate skin lesions suspicious for melanoma in camera-based images as a potential decision-support tool.
The association between cumulative exposure to indoor tanning and the risk for cutaneous squamous cell carcinoma did not vary regardless of age at initiation and duration of use.
Second opinions rendered by dermatopathologists improve the reliability of melanocytic lesion diagnosis, although there is still discordance among pathologists.
In patients with advanced melanoma, sustained long-term overall survival at 5 years was greater in patients who received nivolumab plus ipilimumab or nivolumab alone than in those who received only ipilimumab.
Recommendations for the appropriate use of non-invasive techniques for facilitating melanoma detection have been generated by a committee of dermato-oncologists.
(18F) 2-fluorodeoxyglucose positron emission tomography/computed tomography showed high sensitivity in the detection of recurrent cutaneous squamous cell carcinoma.
Treatment of early stage invasive melanoma with Mohs micrographic surgery was associated with moderately improved overall survival compared with traditional wide margin excision.
