Blood-Based Test May Establish a ‘New Paradigm’ for Cancer Screening
The test can accurately detect cancer and predict where it is located, according to researchers.
Skin Cancer
SKIN CANCER
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Adjuvant Pembrolizumab Prolongs Relapse-Free Survival in Stage II Melanoma
Adjuvant pembrolizumab prolongs relapse-free survival, when compared with placebo, in patients with resected, stage II melanoma.
Oncolytic Therapy Adds No Survival Benefit to PD-1 Treated Advanced Melanoma
Median OS was not reached for the T-VEC plus pembrolizumab arm and 49.2 months for the placebo plus pembrolizumab arm.
Pretreatment Found to Reduce Stages of Mohs Surgery for Basal Cell Carcinoma
A retrospective study evaluated the effect of 5% imiquimod prior to Mohs surgery in patients with basal cell carcinoma.
Gut Bacteria Linked to Immunotherapy Response, Toxicity in Melanoma Patients
Bacteroides intestinalis and Intestinibacter bartlettii were significantly enriched in patients who experienced severe toxicity.
Previous Treatment in Metastatic Melanoma May Cut Response to ACT TIL
Previous treatment with aPD-1 therapy or targeted molecular therapy is associated with a lower objective response rate to adoptive cell transfer of autologous tumor-infiltrating lymphocytes in metastatic melanoma.
Tebentafusp Gets Priority Review for Metastatic Uveal Melanoma
The application is supported by data from the phase 2 IMCgp100-202 trial that assessed tebentafusp in 378 HLA-A*02:01-positive adults with previously untreated metastatic uveal melanoma.
Racial Disparities in Skin Cancer Diagnosis, Prognosis, and Treatment
How significant is the racial disparity in treating patients with skin cancer? Studies in recent years that suggest a troubling difference in the diagnosis and treatment some patients receive. We explore the significant impact this has on patient prognosis.
Dermatologic Adverse Events With Immune Checkpoint Inhibitors in Metastatic Melanoma
Female patients showed an enhanced rate of dermatologic adverse events with immune checkpoint inhibitor therapy for metastatic melanoma.
Real-World Data Finds an Overall Decrease in Pediatric Melanoma Diagnoses in the United States
Researchers studied a total of 1903 cases of pediatric melanoma and patients were 54.4% female, the mean age was 12.4 years, and 89.8% were White.
Fewer Cancers Might Be Missed With Full-Body Skin Examinations
Dermatologist-performed total body skin examinations (TBSEs) identify numerous cutaneous malignancies that might otherwise remain undiagnosed.
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