Rosacea Severity Correlates With Severity of Depression Symptoms

Rosacea on face
Rosacea on face
Investigators utilized the PHQ-9 questionnaire and rosacea self-assessment tool to examine the relationship between the level of depression and self-assessed rosacea severity scores.

Over 31% of patients with rosacea experience depression, and there is a correlation between the disease severity and the depression severity, according to a study published in Cutis.

Researchers examined patients diagnosed with rosacea (N=195) through 2 self-assessed measurements: a rosacea symptom severity survey and the Patient Health Questionnaire 9.  The rosacea survey assessed erythema, papulopustular lesions, ocular symptoms, and nasal involvement, and the Patient Health Questionnaire 9 assessed mental health and mood.

Results indicated that 68.9% of patients were nondepressed, 21.9% had minimal depression symptoms, 7.1% had minor depression, 1.1% had moderate major depression, and 1.1% had severe major depression. There was a direct correlation between rosacea severity and levels of depression (P =.006), meaning an increase in disease severity was associated with an increase in depression severity.

Future studies need to increase study population and diversity to draw more inclusive results.

In conclusion, rosacea is a condition that has a stigma associated with it, and this can have a psychosocial impact on patients, which in turn, can lead to depression.  The level of depression was directly associated with the disease severity. In the future, “[p]hysicians should pay close attention to signs of depression in rosacea patients and determine if psychiatric treatment or referral for psychiatric evaluation is indicated.”


Alinia H, Cardwell LA, Tuchayi SM, et al. Screening for depression in rosacea patientsCutis. 2018; 102(1):36-38.