Psoriasis

PSORIASIS

FEATURE ARTICLE

International Experts Urge Uniformity in Methotrexate Dosing for Psoriasis

Brandon May

An international consensus establishes dosing recommendations of methotrexate for psoriasis treatment and identifies current knowledge gaps on the topic.

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Causal Link Suggested for Psoriasis, Cardiovascular Disease

Evidence suggests a potential causal link for psoriasis and cardiovascular disease (CVD).

Health Care Costs for Psoriasis-Related Anxiety and Depression

Ron Goldberg

Health care costs for systemic treatment patterns and associated anxiety and depression in patients with psoriasis who began conventional systemic treatment are assessed.

Dermatologist Visits Shorter for Asian Psoriasis Patients

Asian patients with psoriasis receive significantly less face-to-face time with a dermatologist than patients of other races and ethnicities.

Zoryve Cream Approved for Plaque Psoriasis

Brian Park, PharmD

The approval was based on data from the two phase 3 trials that included patients aged 12 years and older with mild to severe plaque psoriasis.

Patients With Erythrodermic Psoriasis Find Relief With Golimumab

Ron Goldberg

Researchers report the results of 2 patients with erythrodermic psoriasis–unresponsive to classic therapies–treated with golimumab.

Brodalumab Improves Health-Related Quality of Life for Patients With Plaque Psoriasis

Jessica Nye, PhD

Improvements in health-related quality of life measures in patients with psoriasis treated with brodalumab are assessed.

Psoriasis is a chronic disease that affects 2% to 3% of men and women.2 The disease is characterized by plaques and reddish scaly patches. Some women develop pustular psoriasis, which can be life-threatening if severe.3 Although most women with psoriasis notice symptom improvement during pregnancy, 10% to 20% have symptom deterioration.3 The effect of psoriasis on fetal health is unclear.2 Some studies have suggested that psoriasis, which is a TH1-driven disease, contributes to lower birth weight as observed in other TH1-driven diseases.2 The proposed negative effects of psoriasis on fetal health are usually linked to moderate or severe psoriasis. Topical corticosteroids are safe to use during pregnancy, but topical tar products, tazarotene, and retinoids are teratogenic and should be avoided.2,7 Ultraviolent B phototherapy is safe in pregnant women with moderate to severe psoriasis but may compromise folate levels.2 Limited data are available about the safety of biologics during pregnancy, and careful consideration is required before prescribing.2,7

Long-Term Plaque Psoriasis: Factors Influencing Clinician Decisions

Emily Pond

A novel study identifies significant clinical determinants affecting therapeutic choices in the treatment of long-term plaque psoriasis.

Combination Ultraviolet-Based Phototherapy More Effective at Treating Psoriasis

Jessica Nye, PhD

Various ultraviolet therapies for psoriasis treatment are compared for efficacy and safety.

AI System Could Help Clinicians Assess Psoriasis Severity

An artificial intelligence (AI) system could aid clinicians in assessing psoriasis severity.

Metabolic Syndrome Found in One-Third of Psoriasis Patients Globally

Colby Stong

The prevalence of metabolic syndrome in patients with psoriasis is assessed.

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