Skin barrier dysfunction is a primary mechanism in the production of the common symptoms of atopic dermatitis, including skin dryness, irritation, and itching, and leaves the body vulnerable to allergens and pathogens.
Compared with non-Hispanic white children, Hispanic children were 3.4-fold more likely to have missed at least 6 days of school because of atopic dermatitis.
Short-Form 12 mental component score and Short-Form 6-Dimensional had convergent validity, discriminative validity for atopic dermatitis severity and impact on quality of life, good internal consistency, with no observed floor or ceiling effects for total scores.
Top-line results were announced from a phase 3 study evaluating the safety and efficacy of abrocitinib, an oral Janus kinase 1 (JAK1) inhibitor, for the treatment of moderate to severe atopic dermatitis in patients ≥12 years old.
Researchers identified different phenotypes of atopic dermatitis lesions and their effects on quality of life in adults with atopic dermatitis in the United States.
Atopic dermatitis is associated with a heterogeneous distribution of lesions and several distinct patterns of lesional distribution, which were associated with poorer quality of life.
Investigators sought to determine the effect dupilumab has on patch testing results and improvement of allergic contact dermatitis in patients with allergic dermatitis.
