Healthy Diet Associated With Fewer Facial Wrinkles Among Women

An assortment of fruit
An assortment of fruit
Investigators sought to determine the link between facial wrinkles and diet.

The type of diet consumed by a woman influences the severity of her facial wrinkles, with an unhealthy diet significantly increasing wrinkling and a healthy diet associated with decreased facial wrinkles, according to the results of a population-based, cross-sectional cohort study conducted in The Netherlands and published in the Journal of the American Academy of Dermatology.

The objective of this study was to investigate the link between diet and facial wrinkles in a group of 2753 elderly participants. Wrinkles were digitally quantified as the area in facial photographs that they occupied, calculated as a percentage of the total facial skin area.

Diet was evaluated via use of the Food Frequency Questionnaire Adherence to the Dutch Healthy Diet Index (DHDI). Principal Component Analysis (PCA) was used to extract relevant food patterns among men and women separately. Food patterns and DHDI were analyzed for relationship with wrinkle severity via use of multivariable linear regression.

Median age of the participants was 67.3 years (range, 62.6 to 72.3 years); 59% were women. Known risk factors, including age, gender, body mass index, and smoking status, were significantly associated with wrinkling area in both the basic and the multivariable models. Daily energy intake did not have an impact on wrinkles; however, increased physical activity was associated with more wrinkling in both women and men.

Better adherence to the predefined healthy diet, demonstrated by higher scores on the DHDI, was significantly associated with fewer wrinkles among women (95% CI, -7.30 to -1.08) but not among men. Interestingly, among women, red meat and snack-dominant PCA patterns were significantly linked to more facial wrinkling (95% CI, 0.06-6.68), whereas a fruit-dominant PCA pattern was significantly linked to fewer facial wrinkles
(95% CI, -6.25 to -0.06).

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The investigators concluded that the findings of this study suggest that type of diet influences the severity of facial wrinkling among women, with an unhealthy diet increasing wrinkling and a healthy diet decreasing facial wrinkles. An opportunity is thus created to stimulate adherence to a healthy dietary pattern among women who want to maintain a youthful appearance, which might help lead to improved overall health.


Mekic S, Jacobs LC, Hamer MA, et al. A healthy diet in women is associated with less facial wrinkles in a large Dutch population-based cohort [published online March 27, 2018]. J Am Acad Dermatol. pii: S0190-9622(18)30487-0. doi: 10.1016/j.jaad.2018.03.033