When treatment for acne requires more than topical therapies, systemic treatments may be warranted. John S. Barbieri, MD, discussed with Dermatology Advisor some of the most common mechanisms of acne and how best to address them.
Adalimumab provided significant improvement in patients with HS and possesses a goodsafety profile, which should encourage early use of this treatment to better control disease progression.
The first multisite study of acne prevalence in transgender adults finds that transmasculine individuals are more likely to report moderate to severe acne than are transfeminine individuals.
Spironolactone may be confidently prescribed to women with acne, and a study found that the majority of patients with acne treated with spironolactone had a complete response irrespective of acne severity.
Researchers assessed the incidence of isotretinoin-triggered axial spondyloarthropathy in acne vulgaris patients based on clinical features and MRI findings and examined clinical and radiologic outcomes after drug withdrawal.
Significant improvement in the appearance of acne scars was seen with microneedling or subcision with platelet-rich plasma compared with microneedling or subcision alone.
Chemical peels of more than 1 acid are just as effective as monotherapy for reducing acne lesions and increasing skin hydration — and produce fewer adverse events.
Patients with hidradenitis suppurativa display increased risks for developing ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis, a study finds.
If a second course of therapy is needed, it is not recommended before a 2-month waiting period because the patient’s acne may continue to improve following a 15 to 20-week course of therapy.
