Feature Article

Skin Disease and Metabolic Syndrome: Early Warning Signs of a Greater Problem


Skin disorders, particularly those with known inflammatory mechanisms, may be considered potential early markers for the development of insulin resistance leading to metabolic syndrome, type 2 diabetes, and cardiovascular disease.

The relative risk for healthcare-associated infections has decreased in the last 15 years due to improvements in awareness of risk associated with devices, infection control, and evidence-based practice regarding use of devices.

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Dermatologic Adverse Events Common With Targeted Therapies, Immunotherapies


"Closer collaboration between dermatologists and oncologists is essential," write the authors.

Weak Evidence for Increased Prevalence of Bullous Pemphigoid Among Cancer Patients


Higher incidence rates of subsequent BP have been reported in patients with brain and nervous system tumors than in those with other forms of cancer.

Socioeconomic, Demographic Characteristics Influence Access, Use of Dermatology Outpatient Care

There is an urgent need to characterize these differences further to improve rates of outpatient dermatologic care use in disadvantaged populations.

Quantity of Opioids Prescribed Postop Linked to Consumption

The quantity of opioids prescribed after surgery is associated with patient-reported opioid consumption.

Scoring System May Help Screen High-Risk Patients for Cytomegalovirus Disease, Complications


Investigators sought to determine a scoring system for DiHS/DRESS that may be used to monitor severity and stratify risk for developing CMV disease and complications.

Trichloroacetic Acid Promising for the Treatment of Persistent Oral Mucosal Lesions in Pemphigus Vulgaris


The use of topical trichloroacetic acid 33% as treatment for persistent old refractory oral mucosal lesions in patients with pemphigus vulgaris (PV) may be promising.

Low-Dose Ruxolitinib May Promote Hair Regrowth in Severe Alopecia


Complete or near-complete hair regrowth occurred in 5 patients, with a 98% improvement in the Severity of Alopecia Tool score.

Updated Guidelines Released for Emergency Care of Children

The American Academy of Pediatrics, American College of Emergency Physicians, and Emergency Nurses Association have released updated guidelines for emergency care of injured and critically ill children.

Maternal Age, BMI Among Prenatal Risk Factors Linked to Infant Hemangiomas


Researchers reviewed the charts of 869 mothers and infants —in cases where infants were diagnosed with IH — between January 1, 1976 and December 31, 2010.

FDA-Approved Test Provides Pharmacogenetic Reports Directly to Consumers


The 23andMe Personal Genome Service Pharmacogenetic Reports test can detect 33 variants for multiple genes, corresponding to more than 50 commonly prescribed medications and over-the-counter products.

Oral Dexamethasone May Help Stop or Slow Disease Progression in Non-Segmental Vitiligo


The 2-year retrospective study investigated participants with active non-segmental vitiligo.

Most Supplements Contain Prohibited Stimulants

Many supplements contain one or more stimulants that have been the subject of U.S. Food and Drug Administration-issued public notices.

Variability in Geographic Availability of New Antibiotics

There is considerable variability in the geographic availability of antibiotics.

Light Use of Topical Skin Tx Before Radiotherapy Seems Safe

Contrary to the advice most cancer patients receive, light or moderate use of topical agents before radiation treatment does not appear to increase the radiation dose to the skin.

Disease Extent, Nail Involvement May Predict Clinical Outcomes of Contact Immunotherapy for Alopecia Areata


Hair growth outcomes with contact immunotherapy for alopecia areata were associated with many factors and there was a significant variability in the criteria used.

Clostridium difficile Spores Survive Laundering of Sheets

Clostridium difficile spores are able to survive laundering through a commercial washer extractor.

Personal Care Products: What Patients Should Know About Shaving, Detergents, and More


Detergents labeled as dye- and fragrance-free may be the best option for certain patients.

Treatment for WHIM Syndrome Gets Orphan Drug Designation


X4 Pharmaceuticals is developing the drug, which is currently in a Phase 2/3 clinical trial involving patients with WHIM syndrome.

Topical Cantharidin Safe and Effective for Warts and Molluscum Contagiosum


Topical cantharidin showed high efficacy and safety for the treatment of warts, especially when used with podophyllotoxin and salicylic acid.

Treating Chronic Itch: Therapeutic Review


Itch is "learned" in the nervous system, said Dr Berger, with involvement by both central and peripheral neural processes.

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