CHF and arrhythmias:
Indications for VYNDAQEL:
Treatment in adults with cardiomyopathy of wild type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) to reduce cardiovascular mortality and cardiovascular-related hospitalization.
Swallow whole. 80mg once daily. Not substitutable with Vyndamax on a per mg basis.
Pregnancy. Advise females of reproductive potential to consider pregnancy planning and prevention. Nursing mothers: not recommended.
Transthyretin (TTR) stabilizer.
May potentiate BCRP substrates (eg, methotrexate, rosuvastatin, imatinib).