Migraine and headache:
Indications for: NURTEC ODT
Acute treatment of migraine with or without aura. Preventive treatment of episodic migraine.
Allow tablet to dissolve on tongue. Acute: 75mg once as needed (max daily dose). Preventive: 75mg every other day. The safety of using more than 18 doses in a 30-day period has not been established.
NURTEC ODT Warnings/Precautions:
Discontinue if hypersensitivity reaction occurs; treat appropriately. Severe hepatic impairment (Child-Pugh C) or ESRD (CrCl <15mL/min): avoid. Dialysis: not studied. Pregnancy. Nursing mothers.
NURTEC ODT Classification:
Calcitonin gene-related peptide (CGRP) receptor antagonist.
NURTEC ODT Interactions:
Potentiated by strong CYP3A4 inhibitors (eg, itraconazole); avoid concomitant use. May be potentiated by moderate CYP3A4 or potent P-gp inhibitors (eg, amiodarone, cyclosporine, lapatinib, quinidine, ranolazine). Avoid another dose of Nurtec ODT within 48hrs when used with moderate CYP3A4 or potent P-gp inhibitors. May be antagonized by strong or moderate CYP3A inducers (eg, rifampin); avoid concomitant use.
Nausea; delayed serious hypersensitivity.
Generic Drug Availability: