Feature Article

Atopic Dermatitis: Practical Recommendations for Step-Up Therapy


Although the step-care approach is the current standard of care, this approach is flawed in several ways with respect to achieving optimal outcomes.

The relative risk for healthcare-associated infections has decreased in the last 15 years due to improvements in awareness of risk associated with devices, infection control, and evidence-based practice regarding use of devices.

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Oral Food Challenge Failures Frequent in Patients With Atopic Dermatitis


Investigators examined whether excessive food allergy testing in patients with atopic dermatitis might lead to food intolerance when certain foods are removed from the diet.

Correlation Between Age and Eczema Prevalence Examined

The mean cumulative lifetime prevalence of atopic eczema is 9.9 percent.

Subcutaneous Dupilumab Initiates Hair Regrowth in Patient With Alopecia Totalis, Atopic Dermatitis


Dupilumab, commonly used for eczema, may be effective for hair regrowth in patients with alopecia totalis and atopic dermatitis.

Increased Risk of Depression, Suicide in Atopic Dermatitis


The prevalence of depression in patients with atopic dermatitis was higher than in those without atopic dermatitis.

Treatment for Atopic Dermatitis Generally Decreases During Pregnancy


Generally, women with AD decreased dermatologic therapy during pregnancy.

Dupilumab Gets Priority Review for Adolescent Atopic Dermatitis


Dupixent is also being assessed in other allergic/inflammatory conditions, including pediatric atopic dermatitis, pediatric asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, grass allergy, and peanut allergy.

Prevalence of Atopic Dermatitis 7.3 Percent in U.S. Adults

The prevalence of atopic dermatitis is 7.3 percent among U.S. adults, and patients with atopic dermatitis and more severe disease have worse quality of life.

Ethnic Variations in Molecular Phenotypes of Patients With Atopic Dermatitis


Investigators sought to characterize phenotypic variations in patients with atopic dermatitis who were African American and European American.

Improved Systemic, Cutaneous Abnormalities With Dupilumab in Atopic Dermatitis


Dupilumab reduced cutaneous and systemic measures of inflammation and improved disease-severity scores in 4 weeks in moderate to severe atopic dermatitis.

Atopic Dermatitis Linked to Depression, Anxiety, and Suicidal Ideation


Few available studies investigated the risk of completed suicide; however, most of these found a positive correlation between AD and completed suicide.

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