Feature Article

Atopic Dermatitis: Practical Recommendations for Step-Up Therapy

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Although the step-care approach is the current standard of care, this approach is flawed in several ways with respect to achieving optimal outcomes.

The relative risk for healthcare-associated infections has decreased in the last 15 years due to improvements in awareness of risk associated with devices, infection control, and evidence-based practice regarding use of devices.

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Immunosuppressants Associated With Unsatisfactory Outcomes in Atopic Dermatitis

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Data collection included socio-demographic variables, comorbidities, treatment-related clinical events, immunosuppressant usage, concomitant treatment, and adjustments in dose or type of immunosuppressant.

Molecular Profiles Vary With Age in Atopic Dermatitis

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These findings indicate age-specific treatment approaches would likely benefit patients with atopic dermatitis.

Dupilumab Impacts Symptoms of Atopic Dermatitis in Real-Life Setting

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After 16 weeks of treatment with dupilumab, the median SCORAD score decreased 55%.

Baricitinib Beneficial in Two Phase 3 Atopic Dermatitis Trials

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Baricitinib, a Janus kinase inhibitor, is currently approved under the brand name Olumiant for the treatment of moderately-to-severely active rheumatoid arthritis.

PAC‐14028 Cream Safe, Effective for Mild to Moderate Atopic Dermatitis

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194 participants with mild to moderate atopic dermatitis were randomly assigned to receive vehicle cream or 0.1%, 0.3%, or 1.0% PAC‐14028 cream twice daily.

Link Between Gut Bacteria, Atopic Dermatitis Development

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The investigators sought to determine how the natural environment or diet protects potentially at-risk populations from such allergic conditions as atopic dermatitis.

Thermography Helps Diagnose Allergic vs Irritant Contact Dermatitis

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Researchers sought to determine whether thermography can reliably and effectively distinguish between allergic and irritant contact dermatitis.

Desoximetasone Spray Effective for Treatment-Resistant Psoriasis and Atopic Dermatitis

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Desoximetasone with and without phone reminders was associated with clinical improvement in both psoriasis and atopic dermatitis.

Tapinarof Cream Twice Daily Safe, Effective for Atopic Dermatitis

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The rate of treatment success with tapinarof cream 1% applied twice daily was statistically significantly higher than the rate achieved with vehicle cream.

Weak Association Between Parental Psychiatric Disease and Pediatric Atopic Dermatitis

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Positive but weak associations were found between childhood atopic dermatitis and maternal history of depression, maternal alcohol abuse, and maternal illicit drug use.

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