Feature Article

Atopic Dermatitis: Practical Recommendations for Step-Up Therapy


Although the step-care approach is the current standard of care, this approach is flawed in several ways with respect to achieving optimal outcomes.

The relative risk for healthcare-associated infections has decreased in the last 15 years due to improvements in awareness of risk associated with devices, infection control, and evidence-based practice regarding use of devices.

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Immunosuppressants Associated With Unsatisfactory Outcomes in Atopic Dermatitis


Data collection included socio-demographic variables, comorbidities, treatment-related clinical events, immunosuppressant usage, concomitant treatment, and adjustments in dose or type of immunosuppressant.

Molecular Profiles Vary With Age in Atopic Dermatitis


These findings indicate age-specific treatment approaches would likely benefit patients with atopic dermatitis.

Dupilumab Impacts Symptoms of Atopic Dermatitis in Real-Life Setting


After 16 weeks of treatment with dupilumab, the median SCORAD score decreased 55%.

Baricitinib Beneficial in Two Phase 3 Atopic Dermatitis Trials


Baricitinib, a Janus kinase inhibitor, is currently approved under the brand name Olumiant for the treatment of moderately-to-severely active rheumatoid arthritis.

PAC‐14028 Cream Safe, Effective for Mild to Moderate Atopic Dermatitis


194 participants with mild to moderate atopic dermatitis were randomly assigned to receive vehicle cream or 0.1%, 0.3%, or 1.0% PAC‐14028 cream twice daily.

Link Between Gut Bacteria, Atopic Dermatitis Development


The investigators sought to determine how the natural environment or diet protects potentially at-risk populations from such allergic conditions as atopic dermatitis.

Thermography Helps Diagnose Allergic vs Irritant Contact Dermatitis


Researchers sought to determine whether thermography can reliably and effectively distinguish between allergic and irritant contact dermatitis.

Desoximetasone Spray Effective for Treatment-Resistant Psoriasis and Atopic Dermatitis


Desoximetasone with and without phone reminders was associated with clinical improvement in both psoriasis and atopic dermatitis.

Tapinarof Cream Twice Daily Safe, Effective for Atopic Dermatitis


The rate of treatment success with tapinarof cream 1% applied twice daily was statistically significantly higher than the rate achieved with vehicle cream.

Weak Association Between Parental Psychiatric Disease and Pediatric Atopic Dermatitis


Positive but weak associations were found between childhood atopic dermatitis and maternal history of depression, maternal alcohol abuse, and maternal illicit drug use.

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