Kelly Walkovich Laurence Boxer, Author at Dermatology Advisor

Kelly Walkovich Laurence Boxer

All articles by Kelly Walkovich Laurence Boxer

Chediak-Higashi syndrome

Chédiak-Higashi syndrome What every physician needs to know: Chédiak-Higashi syndrome (CHS) is a rare, autosomal recessive disorder characterized by severe immunodeficiency with frequent bacterial infections, bleeding tendency, decreased pigmentation of hair and eyes (partial albinism), photophobia, nystagmus, progressive neurologic dysfunction, and heightened risk for hemophagocytic histiocytic (HLH) syndrome. Failure of normal granule morphogenesis, resulting in…

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