Hiram de Almeida

All articles by Hiram de Almeida

Stiff Skin Syndrome (Mucopolysaccharidosis)

Are You Confident of the Diagnosis? Stiff skin syndrome is a peculiar condition with sclerodermoid changes, which was described in 1971 by Esterly and McKusic. Skin changes have an early onset in infancy, even from the time of birth, and are characterized by stony-hard skin induration, which is strongly bound, adherent to the deeper underlying…

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