Arielle Davis

Neuroleptic Malignant Syndrome I. What every physician needs to know. Neuroleptic malignant syndrome (NMS) is a rare, potentially fatal complication of treatment with dopamine antagonists (e.g., neuroleptics such as haloperidol) or less commonly acute withdrawal of dopamine agonists (e.g., Parkinson’s medications such as carbidopa-levodopa). The classic clinical presentation is a tetrad of fever, muscle rigidity,…

Primary angiitis of the central nervous system I. Problem/Condition. Cerebral vasculitis is a rare and enigmatic disorder defined by inflammation of the blood vessels of the leptomeninges, brain and/or spinal cord. Inflammation of the cerebral vessels leads to narrowing, occlusion and thrombosis which can then result in ischemia and necrosis. This inflammatory process is typically…