Are You Confident of the Diagnosis? What you should be alert for in the history Determine if the lesions are pruritic. Bullous pemphigoid (BP) is almost always pruritic, and itch can be the first presenting symptom or can herald a relapse. Ask about aggravating factors or associated conditions, which can include stress, ultraviolet radiation or…
Pemphigus vulgaris (ICD-10 code L 10.0) Are You Confident of the Diagnosis? What you should be alert for in the history Determine the scope of mucosal and cutaneous disease: Ask whether patients have pain with eating, swallowing, or sexual intercourse. Ask about aggravating factors, which can include stress, ultraviolet radiation, menses, recent vaccinations, or cessation…
Are You Confident of the Diagnosis? Pemphigus vegetans is considered to be a subset of pemphigus vulgaris. Pemphigus vegetans of Hallopeau has been used to describe a form of indolent disease with good prognosis. Pemphigus vegetans of Neumann is associated with more extensive and refractory disease. What you should be alert fer in the history…
Are You Confident of the Diagnosis? In 1926, Francis Senear and Barney Usher described 11 patients with features of a pemphigus-lupus erythematosus overlap, which they named “pemphigus erythematosus,” later to be known as Senear-Usher syndrome. Subsequently, Walter Lever observed that some patients previously diagnosed as having pemphigus erythematosus in fact had systemic lupus erythematosus, or…
Are You Confident of the Diagnosis? Mucous membrane pemphigoid (MMP) encompasses a group of rare autoimmune blistering diseases that can be relatively difficult to diagnose and manage, reflecting the potential diversity and severity of organ system involvement. The patient may need to consult with several doctors (dermatology, oral medicine, ophthalmology, and otolaryngology most frequently). What…
