Atopic Dermatitis

Genetics, Clinical Characteristics Tied to Atopic Dermatitis Persistence in Childhood

Genetics, Clinical Characteristics Tied to Atopic Dermatitis Persistence in Childhood

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The investigators sought to explore heritable, environmental, and clinical factors linked to persistent atopic dermatitis based on 13 years of follow-up in an at-risk birth cohort.

Risk for Depression and Suicidal Ideation Elevated Among Patients With Atopic Dermatitis

Risk for Depression and Suicidal Ideation Elevated Among Patients With Atopic Dermatitis

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Patients with atopic dermatitis have a higher likelihood of clinical depression and suicidality.

Oral JAK/SYK Inhibitor Granted Fast Track Designation for Atopic Dermatitis

Oral JAK/SYK Inhibitor Granted Fast Track Designation for Atopic Dermatitis

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The Food and Drug Administration (FDA) has granted Fast Track designation to the investigational oral dual inhibitor, ASN002 (Asana BioSciences), for the treatment of moderate-to-severe atopic dermatitis.

Oral Food Challenge Failures Frequent in Patients With Atopic Dermatitis

Oral Food Challenge Failures Frequent in Patients With Atopic Dermatitis

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Investigators examined whether excessive food allergy testing in patients with atopic dermatitis might lead to food intolerance when certain foods are removed from the diet.

Treatment for Atopic Dermatitis Generally Decreases During Pregnancy

Treatment for Atopic Dermatitis Generally Decreases During Pregnancy

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Generally, women with AD decreased dermatologic therapy during pregnancy.

Dupilumab Gets Priority Review for Adolescent Atopic Dermatitis

Dupilumab Gets Priority Review for Adolescent Atopic Dermatitis

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Dupixent is also being assessed in other allergic/inflammatory conditions, including pediatric atopic dermatitis, pediatric asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, grass allergy, and peanut allergy.

Prevalence of Atopic Dermatitis 7.3 Percent in U.S. Adults

Prevalence of Atopic Dermatitis 7.3 Percent in U.S. Adults

The prevalence of atopic dermatitis is 7.3 percent among U.S. adults, and patients with atopic dermatitis and more severe disease have worse quality of life.

Ethnic Variations in Molecular Phenotypes of Patients With Atopic Dermatitis

Ethnic Variations in Molecular Phenotypes of Patients With Atopic Dermatitis

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Investigators sought to characterize phenotypic variations in patients with atopic dermatitis who were African American and European American.

Improved Systemic, Cutaneous Abnormalities With Dupilumab in Atopic Dermatitis

Improved Systemic, Cutaneous Abnormalities With Dupilumab in Atopic Dermatitis

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Dupilumab reduced cutaneous and systemic measures of inflammation and improved disease-severity scores in 4 weeks in moderate to severe atopic dermatitis.

Atopic Dermatitis Linked to Depression, Anxiety, and Suicidal Ideation

Atopic Dermatitis Linked to Depression, Anxiety, and Suicidal Ideation

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Few available studies investigated the risk of completed suicide; however, most of these found a positive correlation between AD and completed suicide.

Early Results Indicate Prolonged Improvements in Atopic Dermatitis With GBR 830

Early Results Indicate Prolonged Improvements in Atopic Dermatitis With GBR 830

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GBR 830 may be an effective and safe long-term treatment option for patients with moderate to severe atopic dermatitis.

Treating Chronic Itch: Therapeutic Review

Treating Chronic Itch: Therapeutic Review

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Itch is "learned" in the nervous system, said Dr Berger, with involvement by both central and peripheral neural processes.

Use of Bee Venom for Topical Treatment in Patients With Atopic Dermatitis

Use of Bee Venom for Topical Treatment in Patients With Atopic Dermatitis

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The use of bee venom and its major component, melittin, has proven suitable as an epicutaneous application for the treatment of atopic dermatitis.

Variation of <i>Staphylococcus aureus</i> Clonal Complex Type Linked to Worse Disease Activity in Atopic Dermatitis

Variation of Staphylococcus aureus Clonal Complex Type Linked to Worse Disease Activity in Atopic Dermatitis

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Of patients who were colonized at both visits, 51.9% remained colonized with the same CC-type at follow-up.

Menthoxypropanediol Provides Itch Relief in Atopic Dermatitis

Menthoxypropanediol Provides Itch Relief in Atopic Dermatitis

The participants were administered a skin care formulation containing menthoxypropanediol.

Hypersensitivity to Allergens in Personal Care Products More Common in Atopic Dermatitis

Hypersensitivity to Allergens in Personal Care Products More Common in Atopic Dermatitis

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Polysensitization was reported significantly more often in patients with atopic dermatitis vs those without.

Individuals With Atopic Dermatitis More Likely to Have Antibody Response to <i>S Aureus</i> Superantigens

Individuals With Atopic Dermatitis More Likely to Have Antibody Response to S Aureus Superantigens

An immunoglobulin E (IgE) antibody response to Staphylococcus aureus superantigens is more common among individuals with atopic dermatitis than healthy controls.

Dupilumab Beneficial in Adolescent Patients With Moderate to Severe Atopic Dermatitis

Dupilumab Beneficial in Adolescent Patients With Moderate to Severe Atopic Dermatitis

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The Phase 3 trial enrolled 251 patients aged 12-17 years old with moderate-to-severe atopic dermatitis, whose disease was not adequately controlled by prescription topical medications or for whom topical treatment was medically inadvisable.

Low Quality of Life, High Disease Burden Seen in Atopic Dermatitis

Low Quality of Life, High Disease Burden Seen in Atopic Dermatitis

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The study findings support the heavy burden that atopic dermatitis places on patients, particularly those with moderate and severe disease.

Stratum Corneum Samples Effective for Immune Response Analysis in Pediatric Atopic Dermatitis

Stratum Corneum Samples Effective for Immune Response Analysis in Pediatric Atopic Dermatitis

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Some aspects of pathophysiologic mechanisms may differ in children with atopic dermatitis with light skin types vs those with dark skin types.

Nemolizumab Effective for Moderate, Severe Atopic Dermatitis Inadequately Controlled With Topical Therapy

Nemolizumab Effective for Moderate, Severe Atopic Dermatitis Inadequately Controlled With Topical Therapy

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For patients with moderate to severe atopic dermatitis inadequately controlled with topical therapies, the anti-IL-31 receptor A humanized monoclonal antibody nemolizumab may provide benefit.

The Association Between Skin Diseases and Metabolic Syndrome

The Association Between Skin Diseases and Metabolic Syndrome

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Investigators examine the association between various skin conditions and metabolic syndrome.

Utility of Antimicrobial Textiles Explored for Atopic Dermatitis

Utility of Antimicrobial Textiles Explored for Atopic Dermatitis

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Functional textiles that rapidly lose their deliverable antimicrobial activity in vitro are not advisable for the AD population.

Atopic Dermatitis Places Heavy Burden on Patients

Atopic Dermatitis Places Heavy Burden on Patients

Atopic dermatitis (AD) dramatically impacts the quality of life of patients.

Pediatric Atopic Dermatitis Associated With Cataract Development

Pediatric Atopic Dermatitis Associated With Cataract Development

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The investigators sought to explore the association of atopic dermatitis with subsequent cataract development and cataract surgery in a Korean pediatric population.

High Patient Burden With Moderate-to-Severe Atopic Dermatitis

High Patient Burden With Moderate-to-Severe Atopic Dermatitis

Patients with moderate/severe atopic dermatitis have higher patient-reported burden than those with mild atopic dermatitis, regardless of disease control.

Severe, Active Atopic Eczema Linked to Increased Cardiovascular Risk

Severe, Active Atopic Eczema Linked to Increased Cardiovascular Risk

The investigators sought to explore whether adults with atopic eczema are at a higher risk for cardiovascular disease, and whether the risk varies based on severity of the disease and the activity of the condition over time.

Elevated Risk of Osteoporosis, Osteopenia in Adults With Atopic Dermatitis

Elevated Risk of Osteoporosis, Osteopenia in Adults With Atopic Dermatitis

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Patients with atopic dermatitis should be encouraged to increase their level of physical activity, partake in adequate weight-bearing exercises, and have a sufficient intake of calcium and vitamin D.

Cold Weather Prompts More Health Care Utilization in Atopic Dermatitis

Cold Weather Prompts More Health Care Utilization in Atopic Dermatitis

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In AD, associations between AD healthcare utilization and hours of cloud cover were generally positive, whereas hours of bright sunlight were generally inversely associated with health care utilization.

Positive Results for Dupilumab in Teen Atopic Dermatitis Trial

Positive Results for Dupilumab in Teen Atopic Dermatitis Trial

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The primary endpoint was the proportion of patients with an IGA score of 0 (clear) or 1 (almost clear) at Week 16.

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