Acne Latest News Archive

Daily Application of Minocycline Foam Effective Against Acne Vulgaris

By Dermatology Advisor Contributing Writer

Investigators examine the safety and efficacy of FMX101 4% topical minocycline foam for moderate to severe acne vulgaris.

Combined Use of RCM, OCT Allows for More Accurate Grading of Acne Vulgaris

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Acne lesion morphology was not associated with the severity of an individual's acne.

Seysara Approved for the Treatment of Moderate to Severe Acne Vulgaris

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The approval was based on data from 2 large, multicenter, randomized, double-blind, placebo-controlled Phase 3 trials involving patients with moderate to severe facial acne vulgaris.

Milk Consumption May Be Linked to Severe Acne Risk

By Dermatology Advisor Contributing Writer

Researchers conducted at met-analysis to examine the association between milk consumption and acne risk.

Psychiatric Comorbidity, Self-Injury Common Among Adolescents With Acne

By

The investigators recommend that psychiatric evaluation be part of a routine acne treatment plan among adolescents.

Lower-Dose Spironolactone Effective for Hidradenitis Suppurativa With Tolerability Issues

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Lower doses of spironolactone seem to be effective and may be an appropriate option for those patients with tolerability issues.

Altreno Approved for the Topical Treatment of Acne Vulgaris

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The approval was based on 2 double-blind clinical trials involving 1640 patients 9 years of age and older with moderate to severe acne vulgaris.

Improved Quality of Life in Adolescents With Acne After Educational Initiative

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The researchers theorized that education aimed at adolescents and delivered in a socially normalized group setting would be associated with durable QoL improvements.

Microwave Ablation Device May Worsen Hidradenitis Suppurativa

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Negative clinical outcomes experienced during the recruitment period prompted the researchers to conduct an interim analysis, which resulted in discontinuation of the study.

Myrtacine-Based Cream Reduces Acne Lesions, Erythromycin Cutibacteria

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Following treatment with the Myrtacine®-based cream in patients with acne, no change in total C acnes load was detected.

Innovative Visual Tool for Assessing Burden of Hidradenitis Suppurativa Being Evaluated

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It is hoped that use of the tool will help to improve the management of HS and enhance patients' feeling of control over their illness.

Once-Daily 7.5% Dapsone Gel Safe, Effective for Acne Vulgaris

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Treating dermatologists recorded their observations of baseline acne, treatment tolerability, and patient outcomes.

Apremilast Effective, Safe in Hidradenitis Suppurativa

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Short-term safety and efficacy of apremilast in patients with moderate hidradenitis suppurativa was examined.

Maintenance Therapy Beneficial for Reducing Adult Acne

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Investigators assessed the efficacy of maintenance therapy in adults with acne.

Long-Term Adalimumab Safe, Effective for Hidradenitis Suppurativa

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The investigators sought to evaluate the response to and tolerability of long-term adalimumab use in patients with HS.

Combination YAG Laser Therapy Provides Effective, Sustained Acne Treatment

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After a mean 22.7 months of follow-up, participants showed an 81% reduction in acne lesions, with 60% of participants having 90% or greater reduction.

Azelaic Acid Foam Is a Safe, Effective Treatment for Facial Acne

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The researchers determined efficacy based on the change in facial investigator global assessment and changes in total, inflammatory, and noninflammatory lesion counts between baseline and week 16.

Spironolactone as Effective as Oral Tetracycline Antibiotics for Acne in Women

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The study included women with acne who were started on either spironolactone (n=6684) or an oral tetracycline-class antibiotic (n=31,614) between 2010 and 2016.

Treatment of Hidradenitis Suppurativa With SAPHO Syndrome: A Case Review

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The male patient presented in 2009 with a "3-year history of multiple interconnecting comedones in the axilla and inguinal regions, as well as scarring from previous lesions."

5-Aminolevulinic Acid 5% Thermosetting Gel Photodynamic Therapy Effective, Tolerable for Inflammatory Acne

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The investigators sought to evaluate the efficacy, safety, and tolerability of red-light (630 nm) PDT with a new 5-aminolevulinic acid "low-dose" topical gel formulation (5%) for the treatment of patients with inflammatory mild to moderate acne vulgaris.

Adalimumab Reduces Skin Pain in Hidradenitis Suppurativa

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Outcomes were examined in 2 randomized, double-blind, placebo-controlled, parallel-group clinical trials: PIONEER I (ClinicalTrials.gov identifier: NCT01468207) and PIONEER II (ClinicalTrials.gov identifier: NCT01468233).

Strong Link Observed Between Hidradenitis Suppurativa, Crohn Disease

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Patients with hidradenitis suppurativa are at an increased risk for the development of Crohn disease.

Hormonal Anti-Androgen Therapy Good Alternative to Systemic Antibiotics in Acne

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Although HAAT is not typically used as a first-line systemic therapy in women with acne, HAAT usage is linked to shorter cumulative antibiotic duration.

Benzoyl Peroxide for Acne More Likely to Stain Cotton/Linen vs Synthetic Fabrics

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The investigators selected 6 different black fabrics for analysis: 100% polyester fleece (100% polyester), 100% cotton, 75% nylon/25% spandex, 100% rayon, and 55% linen/45% rayon.

Education, EMR Tool Improve Acne Treatment Among Pediatricians

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Adherence to guidelines on the part of pediatricians who care for patients with acne has the potential to improve treatment provided in the primary care setting, enhance patient satisfaction, and permit greater access to dermatologists and pediatric dermatologists.

Oral Isotretinoin for Acne Has Substantial Effect on Health-Related Quality of Life

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Dermatology-specific and acne-specific instruments have better sensitivity in assessing successful treatment interventions than generic instruments.

High Rate of Hidradenitis Suppurativa Observed in Patients With Axial Spondyloarthritis

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Hidradenitis suppurativa is more common in patients with axial spondyloarthritis compared with the general population.

Low Glycemic Index/Glycemic Load Decreases IGF-1 Levels in Adults With Acne

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Medical nutrition therapy may be a practical treatment option for patients with acne, based on the diet-induced endocrine effects on acne-promoting pathways described in this study.

Atrophic Scar Formation in Acne Linked to Long-Acting Immune Responses

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Investigators sought to examine the pathophysiology of scar formation among patients with acne.

Combo Therapy Appears Safe, Effective for Severe Inflammatory Acne

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Treatment with the combination gel + oral doxycycline was associated with a 66.2% reduction in inflammatory lesions, a 58.7% reduction in non-inflammatory lesions, and a 62.6% reduction in total lesions at Week 12 vs baseline (P <.0001).

Hidradenitis Suppurativa Disease Severity Not Influenced by Early or Adult-Onset

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Patients with early-onset hidradenitis suppurativa should be reassured by the fact that no difference in the severity of hidradenitis suppurativa was observed between those with onset of disease at ≤17 years of age and those with onset during their adult years.

Microneedling to Treat Acne Scars in Patients With Dark Skin Color

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Microneedling may be an effective treatment for acne scars and hyperpigmentation in patients with dark skin color.

Hormonal Antiandrogen Therapy for Acne May Help Reduce Antibiotic Use

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Recognizing the increased need for antibiotic stewardship, the researchers consider HAAT to be a useful alternative to systemic antibiotic therapy that is effective and well tolerated among women with inflammatory acne.

Acne Scars Reduced, Prevented With Topical Adapalene/Benzoyl Peroxide

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Additional studies are warranted, particularly among those with severe acne, confirm these results and evaluate the best treatment regimen for further reducing atrophic acne scars.

Combination Therapy for Acne May Be Good Alternative to Isotretinoin

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On subject questionnaire, 83.2% participants reported being "satisfied" or "very satisfied" with study treatment, and 90.2% subjects reported moderate symptomatic improvement.

Sarecycline Safe, Effective for Treatment of Acne Vulgaris

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Although this study is limited by its small sample size, the evidence suggests that oral sarecycline 1.5 mg/kg administered once daily may be a viable treatment option for moderate to severe acne.

Assessment of Quality of Life in Acne a Key Component to Disease Management

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An association between impaired QoL in patients with acne and significant psychological problems was consistently noted.

Psychiatric, Somatic Comorbidities Common in Hidradenitis Suppurativa

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Among the somatic comorbidities evaluated were acne, type 1 diabetes, Down syndrome, hypertension, inflammatory bowel diseases, inflammatory joint diseases, metabolic syndrome, obesity, pilonidal sinus, and thyroid disorders.

Warning Patients About Medication Cost May Help Improve Acne Treatment Adherence

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Physician-level interventions designed to improve primary adherence with acne medications may have an impact on nonadherence with expensive medications.

Superficial Chemical Peels Generally Safe in Darker Skin Types

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The investigators sought to determine the frequency of complications and adverse effects linked to the use of superficial chemical peels in patients with skin types III to VI.

Patients Rate Blunt Cannula Subcision Best for Acne Scars

After three months of treatment, patients satisfied with blunt cannula subcision but not Nokor needle subcision.

Hidradenitis Suppurativa Associated With Insulin Resistance

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The study results suggest that hidradenitis suppurativa is both a cutaneous disease and a chronic systemic inflammatory condition.

Tape-Stripping Method Shows Promise for Detecting Acne Vulgaris Changes

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The results obtained from the study were not deemed to be sufficiently valid to predict acne symptoms, since aberrant expression of these skin proteins must indicate some specific tissue conditions.

Risk for Opioid, Alcohol, Cannabis Misuse Greater in Hidradenitis Suppurativa

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Since patients with HS have a higher risk for SUD, periodic screening for substance abuse may be beneficial in this population.

Exploring Nonadherence to Isotretinoin Treatment in Acne

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Close attention to first month follow-up via telephone and message reminders may help increase the successful initiation and completion of isotretinoin treatment.

Risk for Polycystic Ovary Syndrome Linked to Hidradenitis Suppurativa

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The role played by androgens in HS and the potential benefit of anti-androgen treatment in these patients warrants additional investigation.

Acne Associated With Increased Risk for Major Depressive Disorder

These findings suggest that physicians and dermatologists monitor mood symptoms in patients with acne and refer patients to a psychiatrist when needed.

Digital vs In-Person Acne Evaluation: Is Teledermatology Reliable?

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The small pilot study indicates that teledermatology can be a reliable clinical tool that may improve access to dermatologic care.

FDA Will Review Sarecycline for Moderate to Severe Acne

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The Food and Drug Administration has accepted for review the New Drug Application for a once-daily medication for the treatment of moderate to severe acne vulgaris in patients ≥9 years of age.

Long-Term Macrolide Treatment for Acne Increases P. Acnes Resistance

Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes.

Patients With Acne Have High Serum Homocysteine Levels

The researchers found that in both male and female patients, serum homocysteine levels were significantly higher compared to the healthy control group.

Resilience Preserves Quality of Life in Patients With Hidradenitis Suppurativa and Depression

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The opportunity exists to develop resiliency training programs and to explore their role in mitigating stress levels and depressive symptoms among patients with HS.

Consensus Statement on Effective Acne Management: Global Alliance to Improve Outcomes in Acne

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An international group of expert dermatologists with an interest in acne research and education have developed a consensus statement on the effective management of acne.

No Link Found Between Acne, Malignant Melanoma in Men

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Individuals categorized as overweight or obese had a significantly increased risk for malignant melanoma.

Risk of Diabetes Increased in Hidradenitis Suppurativa

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Clinicians should be aware of this increased prevalence and properly screen their patients.

Acne, Sexual Orientation Associated With Mental Health Status

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Nearly one-third of this population report a history of depression and suicidal ideation.

Acne Scarring Improved With Glycolic Acid Peel, Microneedling Combination

Sequential 70% glycolic acid peel and microneedling together have better results for acne scarring.

Managing Comorbidities in Hidradenitis Suppurativa: Expert Recommendations

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Dermatologists should reinforce recommendations for a healthy lifestyle in patients with hidradenitis suppurativa.

Hidradenitis Suppurativa Symptoms Improved With Intravenous Ertapenem

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A 6- to 12-week course of intravenous ertapenem was shown to result in immediate improvement of hidradenitis suppurativa symptoms for all patients and in varying rates of durable response following treatment completion.

Concurrent Isotretinoin Therapy, Dietary Supplementation Associated With Liver Toxicity

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With the use of dietary supplements increasing in adolescents, physicians should be sure to counsel patients on the risks of concurrent use with isotretinoin treatment.

Serum Markers May Predict Acne Scarring

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The identification markers may help in configurating the therapeutic plan to start aggressive treatment in patients prone to scar formation.

Practice Points to Stem Tide of Looming P. acnes Resistance

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Antibiotic use, particularly use of bacteriostatic antibiotics such as erythromycin and clindamycin, is resulting in P. acnes resistance.

Oxidative Stress Not Linked to Acne-Related Depression, Anxiety

Oxidative stress is not related to high levels of anxiety or depression in patients with facial acne.

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