Although the step-care approach is the current standard of care, this approach is flawed in several ways with respect to achieving optimal outcomes.
Methotrexate and azathioprine appear to be effective and safe as maintenance treatments in moderate-to-severe atopic dermatitis for up to 5 years.
Researchers advise dermatologists to discuss the importance of skin examinations and sunscreen use with patients with atopic dermatitis, who are an an increased risk of squamous cell carcinoma.
For patients with chronic palmar hand eczema, both psoralen ultraviolet A and narrowband ultraviolet B treatment improve the severity of the disease.
Despite an increased prevalence, researchers found no significant evidence indicating atopic dermatitis as an independent risk factor for cardiometabolic disease.
Dupilumab Plus Concomitant Topical Corticosteroids Effective for Treatment-Refractory Atopic Dermatitis
Patients with treatment-refractory atopic dermatitis may have good response to dupilumab plus concomitant topical corticosteroids.
In young children, atopic dermatitis severity is linked to an immunoglobulin response directed against Staphylococcus aureus antigens with mainly immune-modulatory functions.
Chronic Spontaneous Urticaria Disease Activity, Treatment Response Linked to C-Reactive Protein Levels
C-reactive protein levels are frequently elevated in patients with chronic spontaneous urticaria, and these elevations are relevant and potentially useful in management of the condition.
Inadequately controlled patients had worse disease-specific quality of life, higher level of work impairment, greater itch, and more sleep interference with daily living.
Prolonged and exclusive breastfeeding may reduce the risk of flexural dermatitis in adolescence, but does not affect lung function or questionnaire-derived measures of asthma or atopic eczema.
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